Lumbar degenerative diseases
Conditions
Interventions
OLIF-BCAAS:Undergoing Oblique lateral interbody fusion with bone cement-augmented anterolateral screws
OLIF-PIFPS:Undergoing Oblique lateral interbody fusion combined with posterior internal fixation with pedicle screws
Sponsors
The People's Hospital of Guangxi Zhuang Autonomous Region
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: a. Adult patients meet the diagnostic criteria for lumbar spinal stenosis combined with lumbar instability. b. Dual-energy X-ray indicates that the bone density T-score of the surgically responsible segment of the lumbar vertebrae is less than -2.5 standard deviations. c. There are surgical indications for single-segment lumbar fusion and a willingness to undergo surgery. d. Willing to participate in this study, fully informed and consent to the research content, and able to cooperate for evaluation and data collection at different follow-up points. e. The research will be conducted at the Department of Spinal Surgery, Guangxi Zhuang Autonomous Region People’s Hospital. The study period is from January 2024 to December 2026.
Exclusion criteria
Exclusion criteria: a. Not suitable for undergoing OLIF (Oblique Lumbar Interbody Fusion) due to conditions such as central canal stenosis of the lumbar spine, extruded intervertebral disc herniation, and grade II or higher spondylolisthesis. b. Multiple underlying diseases that make the patient unable to tolerate surgery/anesthesia. c. Concurrent presence of other conditions causing lumbar back pain, lower limb functional impairment, or other diseases that may affect the assessment of treatment efficacy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale;Oswestry disability index;Japanese Orthopaedic Association scores;Interveterbral disc height; | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation duration;Intraoperative blood loss;Length of surgical incision;Duration of hospitalization;Complications; | — |
Countries
China
Contacts
Public ContactWei Jianxun
The People's Hospital of Guangxi Zhuang Autonomous Region
Outcome results
None listed