Anesthesia of ERCP
Conditions
Interventions
A group:The induction dose of remimazolam is 0.25µg/kg, the maintenance dose is 1mg/kg/h, and 0.2mg of flumazenil is given at the end of the operation.
B group:The induction dose of propofol is 2mg/kg, and the maintenance dose is 6mg/kg/h.
Sponsors
Weifang People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Conduct ERCP on a scheduled basis; 2. Age range from 65 to 85 years old, regardless of gender; 3. ASA is classified as Grade II-III; 4. BMI 18-28kg/m^2. 5.No obvious abnormalities in liver,kidney and lung function.
Exclusion criteria
Exclusion criteria: 1. Proposed Tracheal intubation (including laryngeal mask airway); 2. Severe cardiovascular disease, severe respiratory disease, history of long-term use of psychotropic drugs and cognitive impairment, improved Mallampati rating of IV, history of drug abuse, drug use, and alcohol abuse; 3. Have not received formal antihypertensive treatment or have poor blood pressure control (SBP>=180 mmHg or=100mmH), have allergies or contraindications to opioid drugs, remimazolam, and other drugs and their components, and have participated in other clinical trials as a subject within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of recovery from anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Respiratory depression;Heart rate;Postoperative naused and vomiting;Somatic reaction;Satisfaction of operating doctors; | — |
Countries
China
Contacts
Public ContactGu Xiuxia
Weifang People's Hospital of Shandong Province
Outcome results
None listed