LGI1 encephalitis
Conditions
Interventions
Patients with LGI1 encephalitis group:none
Normal control group:none
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients with LGI1 encephalitis: (1) meet the diagnostic criteria in the Expert Consensus on Diagnosis and Treatment of Autoimmune encephalitis proposed by the Chinese Medical Association in 2022; (2) Patients with positive LGI1 antibody detected in cerebrospinal fluid and/or serum; (3) At least 1 video EEG monitoring; (4) Have relatively complete medical records; Normal control: (1) Healthy individuals whose gender and age match the patient; (2) All participants underwent neuropsychological assessment, 3D T1 MRI, and EEG examination;
Exclusion criteria
Exclusion criteria: (1) central nervous system infectious diseases, demyelinating diseases, tumors or metastases, toxic metabolic encephalopathy, peripheral neuropathy, cerebrovascular disease; (2) Patients with prior primary mental illness; (3) Incomplete case data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cerebrospinal fluid indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serological test indicators;EEG and imaging results; | — |
Countries
China
Contacts
Public ContactYang Zhao
The First Hospital of Jilin University
Outcome results
None listed