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Integrated Multi-omics Study on Blood Biomarkers and Risk Prediction Model for Perioperative Neurocognitive Disorders in the Elderly

Integrated Multi-omics Study on Blood Biomarkers and Risk Prediction Model for Perioperative Neurocognitive Disorders in the Elderly

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096293
Enrollment
Unknown
Registered
2025-01-21
Start date
2025-03-07
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative neurocognitive disorder

Interventions

Postoperative Neurocognitive Disorder Group:None

Sponsors

Department of Anesthesiology, Drum Tower Hospital, Medical School of Nanjing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 65 years; 2. Scheduled for elective surgery.

Exclusion criteria

Exclusion criteria: 1. Refusal to participate in this study; 2. Underwent surgery within the past 3 months; 3. Terminal illnesses (e.g., malignant tumors, severe hepatic or renal dysfunction, cerebrovascular or cardiovascular events); 4. Preoperative Mini-Mental State Examination (MMSE) score 10 times per week) or alcohol withdrawal; 8 Peripheral vascular disease or coagulation disorders that affect blood sampling.

Design outcomes

Primary

MeasureTime frame
Plasma Proteomics;Plasma Metabolomics;—

Countries

China

Contacts

Public ContactXiaoping Gu

Drum Tower Hospital, Medical School of Nanjing University

xiaopinggu@nju.edu.cn+86 138 1399 6903

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026