Hirschsprung's disease
Conditions
Interventions
Left hemicolectomy group:left hemicolectomy
Subtotal colectomy group:subtotal colectomy
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Signed, signed and dated informed consent; 2. Promise to abide by the research procedures and cooperate with the implementation of the whole process of research; 3. Confirmed HD by tissue biopsy before surgery and underwent left hemicolectomy or most of the colonectomy; 4. Except for megacolon, there are no other diseases that affect the evaluation of efficacy; 5. Able to adhere to and cooperate with research follow-up.
Exclusion criteria
Exclusion criteria: 1. Disagree with the study process and be unable to cooperate with the follow-up; 2. Inability to tolerate general anesthesia, coagulation disorders, previous surgical history, severe abdominal adhesions and intestinal obstruction, etc., which are not suitable for minimally invasive surgery; 3. Patients with serious primary diseases such as cardiovascular, liver, kidney and hematopoietic system; 4. Children who are unable to follow up online or in the outpatient clinic of our hospital for a long time due to their own reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative nutritional assessment;Growth and development assessment postoperatively;Postoperative gut microbiota changes;Metabolomic changes of gut microbiota postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complications; | — |
Countries
China
Contacts
Public ContactShaotao Tang
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed