female pattern hair loss
Conditions
Interventions
minoxidil combined with spironolactone:NA
spironolactone:NA
Sponsors
Xiangya Hospital, Central South University
Eligibility
Sex/Gender
Female
Age
12 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Women aged 18-60 years old; 2. clearly diagnosed as female pattern hair loss; 3. Patients received minoxidil combined with spironolactone or spironolactone alone for at least 12 weeks.
Exclusion criteria
Exclusion criteria: Subjects who meet one of the following conditions will not be enrolled in the trial: 1. Known hair loss disorders other than female pattern alopecia, such as alopecia areata or diffuse alopecia areata, alopecia sypetica, cicatricial alopecia, malnutrition, hair loss caused by chemotherapy/radiotherapy; 2. Scalp skin disease affecting the efficacy evaluation, scalp trauma or other scalp skin lesions requiring topical drug treatment, such as fungal or bacterial infection, severe seborrheic dermatitis, scalp psoriasis, contact dermatitis, severe folliculitis or scalp atrophy; 3. Patients with diseases affecting hair growth, such as connective tissue disease, inflammatory bowel disease, moderate to severe anemia, and significant weight loss in the short term; 4. Concurrent treatment with drugs/treatments known to cause hair loss (e.g., isotretinoA, chemotherapy/cytotoxic drugs, head radiotherapy, etc.); 5. Patients without complete treatment and follow-up information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Target Area Hair Counts (TAHC) from baseline to week 12; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in diameter of non-cui hairs, ratio of terminal hairs/cui hairs, and density of hair follicles in the target area;Sinclair rating; | — |
Countries
China
Contacts
Public ContactTang Yan
Xiangya Hospital Central South University
Outcome results
None listed