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Differences in lung function and tumor-related fatigue between SBRT and conventional lung radiotherapy

Differences in lung function and tumor-related fatigue between SBRT and conventional lung radiotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096250
Enrollment
Unknown
Registered
2025-01-21
Start date
2025-01-24
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tumor

Interventions

Observation group:None

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) It meets the indication of lung cancer radiotherapy and can be treated with ordinary lung radiotherapy or SBRT; (2) Patients with ECOG score of 0-1. Grade 0 mobility is completely normal and does not differ from pre-onset mobility. Level 1 can move around freely and engage in physical activity, including general household or office work, but cannot engage in heavier physical activity. (3) Normal cognitive function, language expression ability or reading ability, able to complete the research related questionnaires independently; (4) cardiopulmonary function requirements: no myocardial infarction, stroke, shock within 3 months, acute myocardial infarction within 7 to 10 days, coronary angioplasty 110 times /min, systolic blood pressure >160 mmHg, diastolic blood pressure >100 mmHg, etc (5) Patients and their families fully understand the test and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) The critically ill (serious heart, brain, kidney and other diseases) or other serious medical diseases, such as heart dysfunction, respiratory failure; (2) Combined with lung infection, or there is a long history of smoking, lung function is significantly poor; (3) have been using prescription stimulants or other drugs or health products with clear anti-fatigue effects; (4) There are contraindications to the six-minute walk test. Absolute contraindications include unstable angina pectoris or myocardial infarction within 1 month, worsening heart failure, acute deep vein thrombosis, pulmonary embolism, pulmonary embolism, myocarditis or endocarditis. Relative contraindications include: resting heart rate over 120 beats/min, systolic blood pressure over 180 mmHg, diastolic blood pressure over 100 mmHg, resting blood oxygen saturation < 85%, etc. (5) The patient has other definite causes of fatigue (such as hypothyroidism, insomnia, uncontrolled pain, moderate to very severe anemia, severe malnutrition, cachexia, etc.); (6) Women during pregnancy or breastfeeding; (7) Patients with poor compliance who are not expected to complete the study as planned.

Design outcomes

Primary

MeasureTime frame
Pulmonary function test;The six-minute walk test;Tumor-related fatigue FACT-F questionnaire;

Countries

China

Contacts

Public ContactSun Yu

West China Hospital of Sichuan University

55880810@qq.com+86 134 0841 8719

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026