Tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) It meets the indication of lung cancer radiotherapy and can be treated with ordinary lung radiotherapy or SBRT; (2) Patients with ECOG score of 0-1. Grade 0 mobility is completely normal and does not differ from pre-onset mobility. Level 1 can move around freely and engage in physical activity, including general household or office work, but cannot engage in heavier physical activity. (3) Normal cognitive function, language expression ability or reading ability, able to complete the research related questionnaires independently; (4) cardiopulmonary function requirements: no myocardial infarction, stroke, shock within 3 months, acute myocardial infarction within 7 to 10 days, coronary angioplasty 110 times /min, systolic blood pressure >160 mmHg, diastolic blood pressure >100 mmHg, etc (5) Patients and their families fully understand the test and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) The critically ill (serious heart, brain, kidney and other diseases) or other serious medical diseases, such as heart dysfunction, respiratory failure; (2) Combined with lung infection, or there is a long history of smoking, lung function is significantly poor; (3) have been using prescription stimulants or other drugs or health products with clear anti-fatigue effects; (4) There are contraindications to the six-minute walk test. Absolute contraindications include unstable angina pectoris or myocardial infarction within 1 month, worsening heart failure, acute deep vein thrombosis, pulmonary embolism, pulmonary embolism, myocarditis or endocarditis. Relative contraindications include: resting heart rate over 120 beats/min, systolic blood pressure over 180 mmHg, diastolic blood pressure over 100 mmHg, resting blood oxygen saturation < 85%, etc. (5) The patient has other definite causes of fatigue (such as hypothyroidism, insomnia, uncontrolled pain, moderate to very severe anemia, severe malnutrition, cachexia, etc.); (6) Women during pregnancy or breastfeeding; (7) Patients with poor compliance who are not expected to complete the study as planned.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function test;The six-minute walk test;Tumor-related fatigue FACT-F questionnaire; | — |
Countries
China
Contacts
West China Hospital of Sichuan University