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The Metabolomics of dexmedetomidine for parturients and fetuses undergoing cesarean section

The Metabolomics of dexmedetomidine for parturients and fetuses undergoing cesarean section

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096233
Enrollment
Unknown
Registered
2025-01-20
Start date
2025-01-20
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstetrical anesthesia

Interventions

CON group:In the CON group isovolumic normal saline was infused for 10 min with an intravenous infusion pump.
DEX group:In the DEX group, a loading dose of DEX 0.4 µg/kg was infused for 10 min with an intravenous infusion pump.

Sponsors

Tianjin Center Obstetrics and Gynecology Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 45 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria of this study were: full-term pregnant women undergoing elective cesarean section under neuraxial anesthesia, aged 25 ~ 45 years, weighed 61 ~ 95 kg, ASA physical status II.

Exclusion criteria

Exclusion criteria: The exclusion criteria were parturient refusal, multiple pregnancies, systemic diseases (e.g. cardiac, pulmonary, renal, hepatic, or neurological disorders, and diabetes mellitus), bradycardia, pregnancy-induced hypertension syndrome, fetal distress, fetal cardiac malformation.

Design outcomes

Primary

MeasureTime frame
Untargeted metabolomics;

Secondary

MeasureTime frame
Blood gas analysis;

Countries

China

Contacts

Public ContactQian Li

Tianjin Center Obstetrics and Gynecology Hospital

sapphire-lee@163.com+86 150 2210 9310

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026