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Investigation on the status of perfluorinated and polyfluoroalkyl compound exposure and its effect on cognitive function in the elderly population in Zhuhai area

Investigation on the status of perfluorinated and polyfluoroalkyl compound exposure and its effect on cognitive function in the elderly population in Zhuhai area

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096231
Enrollment
Unknown
Registered
2025-01-20
Start date
2025-01-20
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment

Interventions

Observation group:None

Sponsors

Zhuhai People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnostic criteria: Using the MoCA scale, the boundaries of the cultural level of the study subjects were used as the criteria: illiterate (less than 1 year of education) with a cut-off of 13 points; primary school (between 1-6 years of schooling) with a cut-off of 19 points; Junior high school education level or above (7 years of schooling or more) with a cut-off of 24 points, and a study subject with a score below or above can be assessed as MCI. Inclusion Criteria: Inclusion of the permanent population over the age of 55, living in the community, who are mentally clear and have a certain ability to understand and cooperate, voluntarily participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: Excluded individuals with mental illness, congenital or acquired mental retardation, and inability to perform basic activities of daily living.

Design outcomes

Primary

MeasureTime frame
Per- and polyfluoroalkyl substance (PFAS) levels;Correlation between PFAS levels and the risk of mild cognitive impairment (MCI).;

Secondary

MeasureTime frame
Factors influencing PFAS levels;

Countries

China

Contacts

Public ContactYao Deng

Zhuhai People's Hospital

51658613@qq.com+86 756 2158211

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026