Congenital heart disease
Conditions
Interventions
Control group:General anesthesia induced fentanyl 2ug/kg+ propofol 2.5mg/kg
Experimental group:General anesthesia was induced with esketamine 1mg/kg.
Sponsors
Chinese People's Liberation Army Northern Theater Command General Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 10 Years
Inclusion criteria
Inclusion criteria: 1. Children with congenital heart disease undergoing interventional sealing under elective general anesthesia; 2. Age 1-10 years old; 3. American Society of Anesthesiologists (ASA) Grade II; 4. Patients or guardians fully understand the trial protocol and purpose and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Have a history of mental illness or symptoms of mental illness; 2. History of heart failure within the last 6 months; 3. Severe pulmonary hypertension (pulmonary systolic pressure >=70mmHg); 4. Liver and kidney insufficiency; 5. The experiment involved drug allergy; 6. Need muscular medication or mechanical ventilation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of respiratory depressions and the number of airway interventions given; | — |
Countries
China
Contacts
Public ContactSun Yingjie
Chinese People's Liberation Army Northern Theater Command General Hospital
Outcome results
None listed