Cognitive impairment in high-altitude areas
Conditions
Interventions
Beijing Area Investigation Group:NA
Xining Area Investigation Group:NA
Yushu Area Investigation Group:NA
Sponsors
Qinghai Provincial Transportation Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) People who have lived for more than 6 months at different altitudes (Beijing, Xining, and Yushu); (2) Middle school or above education level; (3) Age range: 18-60 years old; (4) Sign the informed consent form; (5) In addition to the normal population, each group included 40 patients with mild oxygen saturation abnormalities (SPO2=85% to 92%), such as those with sleep apnea syndrome, chronic bronchitis, and long-term smoking.
Exclusion criteria
Exclusion criteria: (1) Combined diagnosis of neurological disorders such as stroke; (2) History of major anesthesia surgeries lasting more than two hours; (3) Combined diagnosis of high altitude diseases such as hypererythema, pulmonary arterial hypertension, heart failure, and COPD; (4) Individuals with previous dementia or cognitive impairment. (5)In addition, there are 1) patients who are currently participating in other clinical trials; 2) Researchers believe that other reasons are not suitable for clinical trial participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rScO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| mini-mental state examination, MMSE;Montreal Cognitive Function Assessment Scale, MoCA; | — |
Countries
China
Contacts
Public ContactLiu Haiyang
Qinghai Provincial Transportation Hospital
Outcome results
None listed