None
Conditions
Interventions
Propofol group:The sedative drug in the induction phase was 3mg/kg propofol, and the analgesic regimen was 0.1ug/kg sufentanil citrate, and the order of administration was as follows: sufentanil, remi
propofol combined with low dose rimazolam:The sedation regimen was 1 mg/kg propofol combined with 0.2 mg/kg remimazolam, and the analgesic regimen was 0.1 ug/kg sufentanil citrate, and the order of ad
propofol combined with high dose rimazolam:The sedation regimen used 1mg/kg propofol combined with 0.4mg/kg remimazolam, and the analgesic regimen used 0.1ug/kg sufentanil citrate, and the order of ad
Sponsors
Capital Medical University Affiliated Beijing Children's Hospital
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. 6 years old ~ 12 years old (including 6 years old and 12 years old); 2. Children undergoing elective combined gastrointestinal endoscopy; 3. ASA Class I~II; 4.BMI <=24.0; 5. Informed consent signed by a parent or legal guardian.
Exclusion criteria
Exclusion criteria: 1. Children with emergency surgery; 2. Patients with severe cardiopulmonary diseases or other organ diseases; 3. Obese children with BMI >=24.0; 4. History of severe allergies or allergy to any drug in the study; 5. Severe obstructive sleep apnea syndrome (obstructive apnea-hypopnea index > 10 times/hour); 6. Children with high reflux aspiration such as active bleeding in the upper gastrointestinal tract; Children whose legal guardians do not sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of blood oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| MABP;Number of movements in the child;Increase the frequency of medication; | — |
Countries
China
Contacts
Public ContactFang Wang
Capital Medical University Affiliated Beijing Children's Hospital
Outcome results
None listed