Chronic thromboembolic pulmonary disease
Conditions
Interventions
Observation group:None
Sponsors
Fuwai Shenzhen Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients who suspected of chronic thromboembolic pulmonary disease (CTEPD) (a.Pulmonary embolism patients have had therapeutic anticoagulation for at least 3 months; b.Still have symptoms; c.Clinical manifestations suggest of CTEPD); 2. With informed consent.
Exclusion criteria
Exclusion criteria: 1. Age75; 2. Severe lung disease (FEV1< 60% predicted); 3. Severe left heart disease, including a. severe mitral stenosis or regurgitation, b. severe aortic stenosis or regurgitation, and c. left ventricular ejection fraction <50%; 4. Contraindications to right heart catheterization and pulmonary angiography (renal insufficiency, uncorrected severe heart failure.); 5. Advanced tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perfusion defect shown by DECT;Sensitivity of DECT for diagnosis;Specificity for the diagnosis of DECT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of perfused blood volume (PBV);DECT thrombosis burden score;Hypercardiac indicators; | — |
Countries
China
Contacts
Public ContactXi Qunying
Fuwai Shenzhen Hospital,Chinese Academy of Medical Sciences
Outcome results
None listed