Atrial Fibrillation
Conditions
Interventions
Sponsors
The First People’s Hospital of Yunnan Province
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Part I (1) Men aged 18-80 years (including 18 and 80 years) or women who are not pregnant or breastfeeding; (2) paroxysmal atrial fibrillation that meets the 2023 ESC AF Management Guidelines recommendation for radiofrequency catheter ablation and receives catheter ablation; (3) Combined Tachychronic syndrome: (1) holter electrocardiogram showed sinus arrest for more than 2 seconds; (2) Holter ECG showed sinus arrest greater than 3 seconds after atrial fibrillation termination; (3) Holter ECG showed an average heart rate of less than 45 beats/min; (4) Fully aware of the study, willing to participate in the study and sign the informed consent. Part Two: (1) Men aged 18-80 years (including 18 and 80 years) or women who are not pregnant or breastfeeding; (2) Persistent atrial fibrillation; (3) Fully aware of the study, willing to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Part I (1) Patients with a life expectancy of less than 2 years due to non-cardiovascular factors; (2) Atrial fibrillation occurs as reversible (electrolyte disturbance, uncontrolled hyperthyroidism, vasovagal reflex, etc.); (3) Previous history of atrial fibrillation ablation; (4) Left atrial diameter greater than 55mm; (5) History of complex structural heart disease; (6) There are radiofrequency ablation, antiarrhythmic or anticoagulation contraindications; (7) Severe hepatic and renal insufficiency; (8) Pregnant or lactating women; (9) any circumstances that the investigator considers likely to cause the patient to be unable to complete the study; (10) Participate in other studies. Part II (1) Patients with a life expectancy of less than 2 years due to non-cardiovascular factors; (2) Atrial fibrillation occurs as reversible (electrolyte disturbance, uncontrolled hyperthyroidism, vasovagal reflex, etc.); (3) History of complex structural heart disease; (4) Severe hepatic and renal insufficiency; (5) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sinus arrest;Pacemaker implantation; | — |
Countries
China
Contacts
Public ContactJie Fan
The First People’s Hospital of Yunnan Province
Outcome results
None listed