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Evaluation of PARP expression by PET-MRI imaging

Evaluation of PARP expression by PET-MRI imaging

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096193
Enrollment
Unknown
Registered
2025-01-20
Start date
2025-02-01
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Interventions

Healthy group:None

Sponsors

The Second Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. For patients with ovarian cancer, breast cancer, pancreatic cancer, or prostate cancer after pathological diagnosis or clinical consideration, solid masses with a minimum of 1.5 cm can be seen by imaging methods. 2. Routine relevant checks have been completed, including the following: (1) 12-lead electrocardiogram, heart B-ultrasound; (2) Laboratory tests: blood routine, urine routine, liver function, kidney function, coagulation routine.

Exclusion criteria

Exclusion criteria: (1) Have participated in other clinical trials within 4 weeks before the start of this study; (2) Those who have no pathological results and no puncture or surgical plan; (3) Suffering from other major diseases (respiratory depression, (lung) airway obstruction or tissue hypoxia, biliary tract diseases, heart diseases, blood system diseases, brain diseases, cognitive impairment); (4) Patients with severe liver and kidney dysfunction (alanine aminotransferase exceeds the upper limit of normal value by 8-10 times, and serum creatinine is 186-442 µmol/L); (5) History of drug allergy, or discontinuation of a drug due to adverse reactions when using a drug; (6) drug and/or alcohol abuse; (7) Pregnant and lactating women; (8) Patients with pacemakers, nerve stimulators, artificial metal heart valves, etc.; Those with aneurysm clips (except for non-paramagnetic such as titanium alloys); Those who have intraocular metal foreign bodies, inner ear implants, metal prostheses, and ferromagnetic foreign bodies in the body.

Design outcomes

Primary

MeasureTime frame
Immunohistochemical score;Standardized Uptake Value maximum, SUVmax;

Countries

China

Contacts

Public ContactXiaowei Ma

The Second Xiangya Hospital of Central South University

maxiaowei@csu.edu.cn+86 151 1119 9770

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026