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An Exploratory Study on the Prognostic Impact of Alveolar Socket Grafting with 'Sticky Bone' on Second Molars with Severe External Root Resorption

A multicenter, prospective randomized controlled trial on the effects of sticky bone filling following mandibular third molar extraction on the prognosis of second molar with external root resorption

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096186
Enrollment
Unknown
Registered
2025-01-20
Start date
2025-06-30
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

External Root Resorption of the Second Molar

Interventions

Control group:Extract the third molar
Experimental group:Extract the third molar and insert the Sticky bone

Sponsors

The Third Affiliated Hospital of Air Force Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. CBCT indicates that the impacted mandibular third molar has caused External Resorption (ERR) of the second molar, with the resorption site located below the crest of the alveolar ridge; 2. The degree of ERR in the second molar is severe; 3. The patient is aged between 18 and 45 years, and the roots of the impacted mandibular third molar are fully developed; 4. The second molar is an erupted permanent tooth that can function normally, with normal pulp vitality and no significant mobility, caries, or large fillings; 5. The subject has chosen to undergo the treatment of extracting the impacted third molar and voluntarily participates in this trial, signing the informed consent form and being able to cooperate with clinical follow-up.

Exclusion criteria

Exclusion criteria: 1. There are cystic lesions, tumors, fractures, osteomyelitis, etc. in the M3 or M2 area of the jawbone; 2. M3 or M2 presents with extensive caries or deformities, crown restoration, distal filling, and root canal treatment of second molars; 3. M3 tooth root not fully developed; 4. Individuals with systemic diseases that cannot withstand tooth extraction surgery; 5. Individuals undergoing orthodontic treatment or having a history of orthodontic treatment; 6. Participated in other clinical trials within the first three months prior to the start of this trial; 7. Pregnant women, lactating women, or patients with a pregnancy plan within six months during menstruation; 8. The patient refuses to have the impacted third molar extracted; 9. Other situations where the doctor determines that participation in the experiment is not possible.

Design outcomes

Primary

MeasureTime frame
Pulp activity of second molar;

Secondary

MeasureTime frame
Priodontal status of second molar;

Countries

China

Contacts

Public ContactZhang Wuyang

The Third Affiliated Hospital of Air Force Medical University

zwyfmmu@163.com+86 187 0685 0527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026