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Effects of bilateral high-frequency repetitive transcranial magnetic stimulation on motor recovery in stroke patients

Effects of bilateral high-frequency repetitive transcranial magnetic stimulation on motor recovery in stroke patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096182
Enrollment
Unknown
Registered
2025-01-20
Start date
2023-09-01
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hemiplegia

Interventions

Bilateral high-frequency group:Bilateral high-frequency repetitive transcranial magnetic stimulation of the brain
Healthy side high-frequency group:High frequency repetitive transcranial magnetic stimulation of the healthy brain
High frequency group on the affected side:High frequency repetitive transcranial magnetic stimulation of the affected brain

Sponsors

First Affiliated Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1: Conforming to the relevant diagnostic criteria in the 2019 Diagnostic Key Points for Various Major Cerebrovascular Diseases in China, stroke was diagnosed through head CT or MRI, with the lesion located under the cortex of the supply area of the unilateral middle cerebral artery, and the initial course of the disease was 2 weeks to 3 months; 2: Age 40-70 years old; 3: Presence of upper limb dysfunction, UE-FMA<60 points; 4: Sign informed consent form.

Exclusion criteria

Exclusion criteria: 1: History of epilepsy; 2: Drug dependence or mental illness; 3: Patients with severe cognitive impairment who are unable to cooperate with treatment; 4: Severe systemic injury or accompanying diseases; 5: Contraindication to TMS (such as metal implants in the brain or the use of pacemakers); 6: Treatment of post-stroke spasm with Muscle relaxant or Botox injection.

Design outcomes

Primary

MeasureTime frame
UE-FMA;

Secondary

MeasureTime frame
Wolf Motor Function Test, WMFT;Motor Evoked Potential, MEP;surface electromyography;Action Research Arm Test, ARAT;Barthel Index;

Countries

China

Contacts

Public ContactYuewen Ma

First Affiliated Hospital of China Medical University

839994984@qq.com+86 180 1892 6323

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026