cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Consent to participate in this study 2. Age >=60 years old 3. Plan to undergo elective coronary artery bypass grafting or valve replacement 4. The expected hospital stay before surgery is 5 days or more
Exclusion criteria
Exclusion criteria: 1. Alzheimer's disease with a MoCA score = 18 points 2. Severe visual or hearing impairment and unable to complete a cognitive function assessment 3. Physical movement disorders and inability to complete cognitive function assessments 4. Claustrophobia and other inability to complete functional MRI examinations 5. Expected survival time is less than one month 6. Other surgeries such as tumor resection at the same time 7. Participating in other clinical trials within three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of delirium within 7 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in cognitive function scores 7 days after surgery;Changes in subjective sleep quality;Incidence of cognitive impairment;Complications and mortality; | — |
Countries
China
Contacts
Peking University Shenzhen Hospital