Autonomic dysfunction and sleep disturbance in critically ill patients
Conditions
Interventions
Continuous feeding group:Provide continuous enteral nutrition support.
Sponsors
Qilu Hospital of Shandong University (Qingdao)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.ICU length of stay after enrollment is expected to be >=5 days. 2.Patients who require enteral nutrition via a nasogastric tube. 3.Age >=18 years, no gender restrictions. 4.Indications for enteral nutrition, with a nutrition risk screening score of 3-7 points. 5.Patients who voluntarily agree or whose family members consent to participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with primary gastrointestinal diseases, such as gastrointestinal ulcers, atrophic gastritis, gastric cancer, etc. 2.Patients who have undergone gastrointestinal surgery. 3.Patients with malignant tumors, end-stage conditions, severe traumatic brain injury, extremely poor prognosis, or those who are likely to die in the short term. 4.Pregnant or breastfeeding women. 5.Patients or their family members who refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate variability (HRV);Sleep Duration and Structure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital sign;Sleep delay time;Awakening frequency;Incidence of delirium;ICU stay;Incidence of complications during hospitalization;Inflammation and immune function; | — |
Countries
China
Contacts
Public ContactBo Yao
Qilu Hospital of Shandong University (Qingdao)
Outcome results
None listed