Postoperative pulmonary complications (PPCs)
Conditions
Interventions
Butorphanol group (Group B):Patients in Group B received a bolus injection of butorphanol 10 µg/kg before induction of anesthesia, followed by a continuous infusion at the rate of 10µg/kg/h until the
Control group (Group C):Patients in Group C were administered an equivalent volume of saline as placebo
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Be between the ages of 18 and 65; (2) American Society of Anesthesiologists (ASA) grades I through III; (3) Patients scheduled to undergo elective thoracoscopic pneumonectomy under general anesthesia.
Exclusion criteria
Exclusion criteria: (1) Body mass index (BMI)>30 kg/m^2; (2) emergency surgery; (3) preoperative use of a ventilator; (4) history of acute lung injury; (5) Acute respiratory distress syndrome or respiratory failure; (6) critical illness, including severe hepatic dysfunction (liver failure or Child-Pugh score B or C); (7) renal failure (SCr>177 µmol/l)); (8) heart failure (New York Heart Association classification > 2); (9) Previous lung surgery; (10) Uncontrolled asthma, forced expiratory volume in 1 second (FEV1) < 60% or contraindication to the use of butorphanol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications (PPCs); | — |
Secondary
| Measure | Time frame |
|---|---|
| The severity grade of PPCs;Unplanned admission to ICU;Total opioid consumption;Postoperative pain level;The quality of recovery;Length of hospital stay; | — |
Countries
China
Contacts
Public ContactSu Liu
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed