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Application of different doses of hydromorphone combined with ropivacaine under ultrasound guidance for caudal block in hemorrhoid surgery.

Application of different doses of hydromorphone combined with ropivacaine under ultrasound guidance for caudal block in hemorrhoid surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096139
Enrollment
Unknown
Registered
2025-01-19
Start date
2025-02-01
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorectal disease

Interventions

L group:Hydromorphone 0.3 mg + 0.75% Ropivacaine 75 mg + 0.9% Sodium Chloride diluted to 20 ml.
M group:Hydromorphone 0.6 mg + 0.75% Ropivacaine 75 mg + 0.9% Sodium Chloride diluted to 20 ml.
H group:Hydromorphone 1 mg + 0.75% Ropivacaine 75 mg + 0.9% Sodium Chloride diluted to 20 ml.

Sponsors

Liuzhou Traditional Chinese Medical Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patient ASA I.-II., age l8~60 years old; 2. BMI normal range (18.5-23.9kg/m^2); 3. The indication for surgery is clear and there are no contraindications to surgery and anesthesia; 4. The surgical method is prone folding knife hemorrhoidectomy; 5. Patients with relatively stable preoperative condition and normal mental consciousness voluntarily participate in this research activity.

Exclusion criteria

Exclusion criteria: 1. Patients with serious primary diseases such as cardiovascular, liver, kidney, brain, lung and hematopoietic system; 2. Those with a history of mental illness and alcohol and drug dependence; 3. Patients with anxiety caused by other organic lesions; 4. Pregnant and lactating females; 5. Those who have a history of allergy to anesthetics in the past; 6. Second surgery; 7. Neuraxial anesthesia contraindications or complications and morphine contraindications; 8. Hypotension, bradycardia (more than moderate HR less than 50 beats/min) and sinus arrest. 5. Rejection criteria 9. Those who have suspended the surgical treatment plan; 10. Those who are discharged from the hospital or die in the middle of the hospital; 11. Withdrawal from the investigator for other reasons; 12. Patients who change the surgical method during surgery.

Design outcomes

Primary

MeasureTime frame
The duration of analgesia;

Secondary

MeasureTime frame
Intraoperative additional opioid consumption;Anesthesia-related complications;Time of onset of anesthesia;Blood pressure and heart rate before and after surgery.;Levels of Efficacy of Intrathecal Anesthesia;

Countries

China

Contacts

Public ContactYijia Zhang

Liuzhou Traditional Chinese Medical Hospital

Zhangyijia200909@163.com+86 152 8962 9395

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026