depression
Conditions
Interventions
Control group (pseudo-stimulation group):RMT low-frequency pseudo stimulus
stimulated group:rTMS treatment
Sponsors
Huzhou Third Municipal Hospital
Eligibility
Sex/Gender
All
Age
14 Years to 28 Years
Inclusion criteria
Inclusion criteria: 1.The patient (or their legal representative/guardian) signs an informed consent form; 2.14 <= Age <=28 years old, gender not limited; 3.Adopting a simplified International Neuropsychiatric Interview (MINI) that meets the diagnostic criteria for DSM-V depressive episodes; 4.Young's Mania Scale (YMRS) <= 6 points; 5.12 points <= Montgomery Depression Scale (MARDS) < 30 points; 6.Right-handed hand; 7.have completed more than 9 years of compulsory education.
Exclusion criteria
Exclusion criteria: 1.History of cognitive loss due to organic brain disease or head trauma; 2.Any significant or unstable history of cardiovascular, respiratory, neurological (including epilepsy or obvious cerebrovascular disease, traumatic brain injury), renal, liver, endocrine or immune diseases, or organic diseases causing anxiety, depression, or other related conditions, or current infection, trauma, etc; 3.Any contraindications of MRI or abnormal brain structure detected by magnetic resonance examination; 4.Individuals with hearing problems (unable to hear or understand the examiner's speech clearly during normal conversation) and vision problems; 5.History of abuse and dependence on psychoactive substances; 6.Long term use of anticholinergic drugs or recent use of anti-inflammatory drugs; 7.Pregnant, lactating women or those planning to conceive; 8.Serious suicidal ideation and behavior or MARDS >= 30 points; 9.Patients who receive ECT or rTMS treatment within six months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montgomery Depression Rating Scale,MARDS;Magnetic resonance data and near-infrared;Adolescent Non-suicidal Self-injury Assessment Questionnaire,ANSAQ;Hamilton Depression Rating Scale (HAMD);Hamilton Anxiety Scale; | — |
Countries
China
Contacts
Public ContactShiliang Wang
Huzhou Third Municipal Hospital
Outcome results
None listed