Acute ischemic stroke
Conditions
Interventions
Thrombolysis group:None
Non thrombolytic group:None
Sponsors
Suzhou Hospital Affiliated to Nanjing University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age>=18 years; (2) Confirmed acute ischemic stroke; (3) Meet the criteria for intravenous thrombolytic therapy in the 2023 edition of the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke; (4) Arrive at the hospital within 4.5 hours after the onset of symptoms; (5) Subject or guardian signs informed consent.
Exclusion criteria
Exclusion criteria: (1) History of major head trauma or stroke in the past 3 months; (2) Intracranial hemorrhage (including parenchymal hemorrhage, intraventricular hemorrhage, subarachnoid hemorrhage, subdural/extradural hematoma, etc.); (3) Arterial puncture of the site that is not easy to compress in the past 1 week; (4) History of previous intracranial hemorrhage; (5) Intracranial tumors, intracranial giant aneurysms; (6) Intracranial or neuraxial surgery in the past 3 months; (7) Major surgery in the past 2 weeks; (8) aortic arch dissection; (9) Active visceral hemorrhage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of modified Rankin Scale (mRS) score <=2 (functional Recovering well); | — |
Secondary
| Measure | Time frame |
|---|---|
| 90-day distribution of mRS score values;Exacerbation within 24 hours (elevated NIHSS >=4 points);Patient mRS score at discharge;Comparison of the effectiveness of the thrombolysis group with other thrombolysis databases in the same period; | — |
Countries
China
Contacts
Public ContactJingwei Li
Department of Neurology, Suzhou Hospital Affiliated to Nanjing University School of Medicine
Outcome results
None listed