Ultrasound-guided intertransverse process block and erector spinal plane block for postoperative analgesia in laparoscopic total hysterectomy:: A double-blind, randomized controlled study.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500096111

Enrollment

Unknown

Registered

2025-01-17

Start date

2024-11-14

Completion date

Unknown

Last updated

2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine fibroids, adenomyosis, endometriosis, etc

Interventions

Group I (intertransverse process block):intertransverse process block

Group E(erector spinal plane block):erector spinal plane block

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective total hysterectomy; 2. aged 18-65 years old; 3. body mass index:19-28kg/m²; 4. American Society of Anesthesiology class (ASA) IIIIII;

Exclusion criteria

Exclusion criteria: 1.Declined to participate in this study; 2. Contraindications for deep nerve blocks,including, but not limited to, allergy to narcotic drugs,coagulopathy (INR > 1.5 and/or platelet count 180mmHg); 4. Long-term oral analgesics; 5. Patients with mental illness or who were unable to complete the rating scale; 6. Nerve block cannot be performed due to the difficulty of ultrasound scanning anatomy.

Design outcomes

Primary

Measure	Time frame
morphine equivalent of opioid consumption within 24 hours after surgery (PACU sufentanil, therapeutic analgesia tramadol);	—

Secondary

Measure	Time frame
intraoperative remifentanil dosage;area under the curve of VAS scores for abdominal wall incision pain and visceral pain during 24h after surgery:when pulling out the endotracheal tube(T0)?2h(T1)?4h(T2)?6h(T3)?8h (T4)?10h(T5)?12h(T6)?1;Satisfaction with anesthesia.;the incidence of perioperative tachycardia,bradycardia,hypertension and hypotension (defined as an increase or decrease in heart rate and MAP by at least 20% of the baseline value);the time of first rescue analgesia and the dose of rescue analgesic drug (tramadol) after sugery;QoR-15 score at 24 h postoperatively;incidence of postoperative complications (nausea, vomiting, pruritus, dizziness and other adverse reactions);;complications associated with the block;time to first postoperative independent movement;Range of sensory block in both groups;	—

Measure

Time frame

intraoperative remifentanil dosage;area under the curve of VAS scores for abdominal wall incision pain and visceral pain during 24h after surgery:when pulling out the endotracheal tube(T0)?2h(T1)?4h(T2)?6h(T3)?8h (T4)?10h(T5)?12h(T6)?1;Satisfaction with anesthesia.;the incidence of perioperative tachycardia,bradycardia,hypertension and hypotension (defined as an increase or decrease in heart rate and MAP by at least 20% of the baseline value);the time of first rescue analgesia and the dose of rescue analgesic drug (tramadol) after sugery;QoR-15 score at 24 h postoperatively;incidence of postoperative complications (nausea, vomiting, pruritus, dizziness and other adverse reactions);;complications associated with the block;time to first postoperative independent movement;Range of sensory block in both groups;

—

Countries

China

Contacts

Public ContactHaiyun Du

Yancheng First People's Hospital

375923019@qq.com+86 13914623809

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026