Syphilis, gonorrhea, chlamydia and human papillomavirus
Conditions
Interventions
Offline secondary distribution group:Offline secondary distribution
Internet-based secondary distribution group:Internet-based secondary distribution
Internet-based secondary distribution with monetary incentives group:Internet-based secondary distribution with monetary incentives
Sponsors
The First Hospital of China Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1. MSM aged 18-30 years old; 2. Self-report at least any of the following: previous participation in the CROPrEP project; Have taken PrEP for more than 1 month; HIV positive. 3. Willing to provide personal contact information for follow-up; 4. Those who are informed about this research protocol, agree to participate in the survey and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. People who are allergic to tetracycline; 2. According to the prescription, taking drugs that may affect doxycycline metabolism or contraindications to doxycycline, including tretinoin, barbiturates, carbamazepine and phenytoin, etc.; 3. Are using anticoagulants such as warfarin; 4. Anticipated use of doxycycline for non-STI prophylaxis (e.g., acne treatment) within the next 12 months; 5. Those who are unwilling to participate in STIs self-sampling; 6. Those who are unwilling to sign the informed consent form; 7. Those who are unwilling to participate in follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of indexes and alters who successfully used the STIs self-sampling kits among the three groups;The average number of successful alters distributed by each index;Incidence rate of STIs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of alters with HIV-reactive results identified by each index;Proportion of indexes and alters who have used doxy-PEP at least once within 72 hours after engaging in risky sexual activity among the three groups;The proportion of indexes who successfully distributed STIs self-sampling kits to at least one alter;Factors associated with STIs detection results;Economic evaluation; | — |
Countries
China
Contacts
Public ContactQinghai Hu
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, NHC Key Laboratory of AIDS Prevention and Treatment, National Clinical Research Center for Laboratory Medicine, The First Hospital of China Medical University
Outcome results
None listed