Dye Eye
Conditions
Interventions
The test group:Combined use of Zirun ? (0.05% cyclosporine eye drops II) and Aiermin ? (0.1% sodium hyaluronate eye drops)
The control group:Ailmin ? alone (0.1% sodium hyaluronate eye drops)
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
10 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Age 10-18 years old; 2. Myopia patients wearing orthokeratology lenses; 3. Complaining of one or more of the subjective symptoms such as eye dryness, foreign body sensation, burning sensation, fatigue, discomfort, eye redness, and vision fluctuations; 4. Fluorescein stained tear film break-up time (FBUT) <=5s; 5. Subjects and their legal guardians can understand the purpose of this trial, are willing to cooperate with treatment and follow-up, voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Eyelid entropion, ectropion, trichiasis, corneal ulcer, trachoma, keratitis, blepharitis/meibomian adenitis, meibonanitis/meibomian cyst, ocular trauma, lesions caused by corneal foreign bodies, burns, dacryocystitis and other infections, etc.; 2. Patients with abnormal intraocular pressure (normal intraocular pressure range is 10~21 mmHg, and the difference in intraocular pressure between the two eyes should be <=5 mmHg); 3. Those who are allergic to the use of drugs; 4. Patients with severe primary diseases and mental disorders such as liver, kidney and hematopoietic system; 5. Those who participate in other clinical validators or those who are considered inappropriate by the investigator to participate in this trial; 6. Those who are unable to follow up on time and do not sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The fluorescein tear breakup time at 3 month; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tear meniscus height;The fluorescein tear breakup time at 1 month;Schirmer I test;Corneal fluorescein staining test;Lissamine green staining test;Ocular redness index;Ocular Surface Disease Index (OSDI) score;Slit lamp test;Intraocular pressure;Visual acuity;Subjective refraction; | — |
Countries
China
Contacts
Public ContactGe Wu
Eye Hospital, Wenzhou Medical University
Outcome results
None listed