Cirrhotic portal hypertension
Conditions
Interventions
Gold Standard:Hepatic venous pressure gradient(HVPG)
Index test:Endoscopic ultrasound-guided portal pressure gradient(EUS-PPG)
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 75 years; 2. Cirrhosis due to various causes, the presence of portal hypertension is suggested by clinical manifestations (e.g., presence of ascites, esophagogastric varices) or by noninvasive methods (e.g., elastosonographic liver stiffness measurement) or invasive methods (HVPG measurement); 3. With complete information; 4. Informed consent was obtained to participate in the study;
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiopulmonary function disorders could not tolerate EUS puncture pressure measurement and interventional procedures; 2. Abnormal coagulation index, international normalized ratio (INR) >1.5 or platelet count <50×109/L, puncture has a high risk of bleeding; 3. Patients who had previously undergone transjugular intrahepatic portosystemic shunt (TIPS); 4. Preoperative anesthesia evaluation was performed routinely, and the results of anesthesia evaluation were those who were not suitable for examination or treatment under general anesthesia; 5. Refusal to participate in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consistency between EUS-PPG measurements and HVPG measurements; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of complication; | — |
Countries
China
Contacts
Public ContactBin Zhou
Peking University First Hospital
Outcome results
None listed