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Multicentre retrospective cohort study of pregnancy outcomes in advanced maternal age

Multicentre retrospective cohort study of pregnancy outcomes in advanced maternal age

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096083
Enrollment
Unknown
Registered
2025-01-17
Start date
2025-01-17
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic disorders of pregnancy

Interventions

Unexposed group (age-appropriate pregnancy):None
Exposed group (advanced gestational age):None

Sponsors

Southern Medical University Southern Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Those who were at delivery between 25-29 years of age or 35 years of age and above. 2. From Nov. 2021-Nov. 2023 attended Nanfang Hospital, Southern Medical University. 3. Hospitalized deliveries with newborns delivered at >=28 weeks gestational age. 4. Singleton pregnancy.

Exclusion criteria

Exclusion criteria: 1. Carriers of infectious diseases such as AIDS, syphilis, and hepatitis B virus; 2. Patients with impaired glucose tolerance or diabetes mellitus before pregnancy; 3. Pregnant patients with hypertension and hyperthyroidism; 4. Pregnant patients with thalassemia and G6PD (Glucose-6-phosphate dehydrogenase) deficiency; 5. There is a family history of Down syndrome and other family genetic history; 6. History of severe organic diseases or tumors such as heart, lung, and brain; 7. History of autoimmune diseases; 8. Long-term exposure to radiation or toxic substances such as lead, mercury, benzene and organophosphorus pesticides in the working environment; 9. Those who have side effects from long-term use of hormonal drugs or those who have drug abuse; 10. Pregnant women who are judged by the investigator to be unsuitable for inclusion in this study.

Design outcomes

Primary

MeasureTime frame
Incidence of metabolic diseases in pregnancy;

Secondary

MeasureTime frame
Maternal clinical characteristics and outcome indicators;Neonatal clinical characteristics and outcome indicators;Placenta and appendages outcome indicators;Indicators of routine prenatal laboratory tests;

Countries

China

Contacts

Public ContactJing Chen

Southern Medical University Southern Hospital

332622858@qq.com+86 20 62787294

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026