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A Multicenter, Observational Study on the Impact of Extraction Versus Non-extraction of Impacted Third Molars on the Prognosis of Second Molars with External Root Resorption

A Multicenter, Observational Study on the Impact of Extraction Versus Non-extraction of Impacted Third Molars on the Prognosis of Second Molars with External Root Resorption

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096040
Enrollment
Unknown
Registered
2025-01-16
Start date
2025-02-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

External Root Resorption of the Second Molar

Interventions

Reserve group:NA
Remove group:NA

Sponsors

The Third Affiliated Hospital of Air Force Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Time Period: From December 1, 2018, to November 30, 2022, patients from various centers were identified with mandibular impacted third molars causing external root resorption (ERR) in the second molars, as evidenced by Cone Beam Computed Tomography (CBCT), with the site of external resorption located below the alveolar crest. 2. Patient Age: Patients aged between 18 and 60 years, with fully developed roots of the impacted mandibular third molars. 3. Condition of the Second Molar: The second molar has erupted and is capable of normal function, without significant mobility, caries, or large areas of restorative material. 4. Patient Participation: Subjects voluntarily participated in this study and were able to return to the hospital for follow-up visits.

Exclusion criteria

Exclusion criteria: 1. There are cystic lesions, tumors, fractures, osteomyelitis, etc. in the M3 or M2 area of the jawbone; 2. M3 or M2 presents with extensive caries or deformities, crown restoration, distal filling, and root canal treatment of second molars; 3. M3 tooth root not fully developed; 4. Individuals with systemic diseases that cannot withstand tooth extraction surgery; 5. Individuals undergoing orthodontic treatment or having a history of orthodontic treatment; 6. Participated in other clinical trials within the first three months prior to the start of this trial; 7. Pregnant women, lactating women, or patients with a pregnancy plan within six months during menstruation; 8. Other situations where the doctor determines that participation in the experiment is not possible.

Design outcomes

Primary

MeasureTime frame
Pulp activity of second molar;

Secondary

MeasureTime frame
Periodontal status of second molars (looseness, periodontal examination);

Countries

China

Contacts

Public ContactZhang Wuyang

The Third Affiliated Hospital of Air Force Medical University

zwyfmmu@163.com+86 187 0685 0527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026