Sleep disorder
Conditions
Interventions
Control group:Equal amounts of 0.9% sodium chloride were received.
Experimental group:0.25 mg/kg esketamine was received.
Sponsors
Xiangyang No.1 People's Hospital,Hubei University of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age 18~80 years old; (2) ASA (American Society of Anesthesiologists) Class I-III; (3) BMI between 18-24kg/m^2; (4) Elective cardiothoracic surgery.
Exclusion criteria
Exclusion criteria: (1) The patient refused to participate in the study; (2) Body mass index above 30; (3) Recent history of drug abuse; (4) Contraindications or allergies to esketamine; (5) Cognitive dysfunction or inability to communicate; (6) Inability to use patient-controlled analgesia pumps.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative sleep disorders; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality (NRS) score on day1, 3, and 5 postoperatively;AIS scores on the 1, 3 and 5 day after surgery;Postoperative static and dynamic pain NRS scores;Preoperative and postoperative anxiety and depression scores;Intraoperative opioid consumption;Relevant indicators in the blood;Content of relevant indicators in saliva;Christense Postoperative Fatigue Scale;Adverse event rate; | — |
Countries
China
Contacts
Public ContactHuiyu Luo
Xiangyang No.1 People's Hospital,Hubei University of Medicine
Outcome results
None listed