HCC
Conditions
Interventions
Sponsors
The Fifth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Cohort A: 1) Age >=18 years old, male or female; 2) HCC patients with CNLC stage IIIa confirmed by histology or meeting the clinical diagnostic criteria (according to the Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2024 edition)); 3) Patients should meet the following HCC classification according to the expert consensus on Refined diagnosis and management of advanced primary liver cancer (2023 version) : a. Stage IIIa1 HCC patients with PS 0-2, Child-Pugh A/B (3 or more than half liver, and no extrahepatic metastasis; c. Stage IIIa3 HCC patients with PS 0-2, Child-PughA/B (=18 years old, male or female; 2) HCC patients with CNLC stage IIIa confirmed by histology or meeting the clinical diagnostic criteria (according to the Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2024 edition)); 3) Child-Pugh =18 years old, male or female; 2) HCC patients with CNLC stage IIIb confirmed by histology or meeting the clinical diagnostic criteria (refer to the Standard of Diagnosis and Treatment of Primary Liver Cancer (2024 edition)); 3) Patients should meet the following HCC classification according to the expert consensus on Refined diagnosis and management of advanced primary liver cancer (2023 version) : A. IIIb1 was defined as stage IIIb1 HCC patients with PS 0-2, Child-Pugh A/B (=18 years old, male or female; 2) HCC patients with CNLC stage IIIb confirmed by histology or meeting the clinical diagnostic criteria (refer to the Standard of Diagnosis and Treatment of Primary Liver Cancer (2024 edition)); 3) Child-Pugh <=7; 4) ECOG PS 0-2.
Exclusion criteria
Exclusion criteria: 1) patients with incomplete follow-up data; 2) had received systemic anti-tumor therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-Free Survival;overall response rate;safety;quality of life;medical expense; | — |
Countries
China
Contacts
Public ContactYinying Lu
The Fifth Medical Center of PLA General Hospital
Outcome results
None listed