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A retrospective, real-world clinical study of prognostic factors in patients with HER-2 mutated non-small cell lung cancer

A retrospective, real-world clinical study of prognostic factors in patients with HER-2 mutated non-small cell lung cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096023
Enrollment
Unknown
Registered
2025-01-16
Start date
2025-01-16
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Case series:None

Sponsors

The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patient age>=18 years, male or female; 2. Non-small cell lung cancer confirmed by histological or cytological pathology; 3. Genetic testing confirms the presence of HER-2 variants, including gene mutations, gene amplification, and protein overexpression; 4. Previously received standard anti-tumor therapy in line with clinical practice and regularly returned to the hospital for reexamination; 5. Inclusion of patients with no or no central nervous system symptoms or signs is allowed.

Exclusion criteria

Exclusion criteria: 1. Concomitant tumors other than NSCLC; 2. Other malignant tumors or history of other malignant tumors within the past 5 years, except for basal cell carcinoma of the skin, carcinoma in situ of the cervix and carcinoma of the duct in situ of the breast that have been effectively controlled.

Design outcomes

Primary

MeasureTime frame
Factors affecting prognosis;

Secondary

MeasureTime frame
Overall survival;Symptom improvement rate;

Countries

China

Contacts

Public ContactQiming Wang

The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital

qimingwang1006@126.com+86 187 0383 7615

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026