Chronic discogenic low back pain
Conditions
Interventions
Trial group:transforaminal intradiscal steroid injection (Transforaminal Intradiscal Steroid Injection, TISI)
Control group:transforaminal epidural steroid injection (Transforaminal Epidural Steroid Injection, TESI)
Sponsors
Beijing Shijitan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Age between 18 and 70 years (2) Duration of low back pain exceeding 3 months (3) Numerical Rating Scale (NRS) >=4. (4) Failure of at least 3 months of standard conservative treatment. (5) Diagnosed as lumbar discogenic low back pain through physical examination and imaging, with MRI showing Modic?changes in the affected disc. (6) No similar injection treatments received within the past 6 months.
Exclusion criteria
Exclusion criteria: (1) Severe spinal deformities, trauma, fractures, lumbar myofascial pain syndrome, lumbar spinal stenosis, lumbar spondylolisthesis, spinal tumors, spinal infections, or inflammatory diseases (2) Pregnancy (3) Allergy to steroids or contrast agents (4) Systemic infectious diseases or localized skin infections at the puncture site (5) Previous interventional procedures or surgeries on the same segment of the intervertebral disc (6) Severe coagulation dysfunction (7) Modic ? changes in multiple lumbar levels of intervertebral disc degeneraton (8) Comorbidity with psychiatric disorders that may impair cooperation (9) Refusal to sign the informed consent form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Low back pain condition; | — |
Secondary
| Measure | Time frame |
|---|---|
| Function of the lumbar Spine;Functional disability caused by low back pain;Quality of life;Psychiatric status assessment;Intervertebral disc calcification;Intervertebral disc height;Degenerative changes of the intervertebral disc; | — |
Countries
China
Contacts
Public ContactJipeng Song
Beijing Shijitan Hospital, Capital Medical University
Outcome results
None listed