Skip to content

Effect of Sugammadex Sodium on postoperative recovery in patients undergoing short surgery - a single-center, prospective, randomized controlled study

Effect of Sugammadex Sodium on postoperative recovery in patients undergoing short surgery - a single-center, prospective, randomized controlled study

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095998
Enrollment
Unknown
Registered
2025-01-16
Start date
2025-02-01
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative recovery

Interventions

Experimental group:At the end of the operation, 2mg/kg sodium suggenose was injected intravenously when TOF>=2
Control group 1:Control group 1 was given neostigmine according to the TOF value. TOF = 2-3, neostigmine 50µg/kg + Atropine 20µg/kg
TOF = 4, TOFR < 0.4, Neosmin 40µg/kg + Atropine 15µg/kg
TOF = 4,0.4 <= TOFR < 0.9, Neosmin 30µg/kg + Atropine 10µg/kg.
Control group 2:At the end of the operation, 5mL of saline was injected intravenously

Sponsors

Affiliated Traditional Chinese Medicine Hospital of Xi'nan Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Age> 18 years old, < 75 years old; 2) ASA classification I-II; 3) elective short surgery with general anesthesia, with an estimated operation duration of <=60 minutes; 4) The patient has good compliance and can cooperate with the treatment; 5) Patient informed consent, and signed informed consent.

Exclusion criteria

Exclusion criteria: 1) Patients with neuromuscular diseases (myasthenia gravis, periodic paralysis, polymyositis, etc.); 2) Lower limb fractures, nerves, blood vessels, tendons and other related surgeries; 3) Preoperative lung disease (pleural effusion, atelectasis, pneumothorax, pulmonary infection, bronchiectasis, COPD, emphysema); 4) Patients who have recently used aminoglycoside antibiotics or other drugs that affect neuromuscular conduction; 5) Patients who have participated in or plan to participate in other clinical studies in the past 3 months; 6) Those who are allergic to sulgammadex sodium, neostigmine, rocuronium bromide and other anesthetics.

Design outcomes

Primary

MeasureTime frame
Principles of Advanced and Distributed Simulation Score;

Secondary

MeasureTime frame
TOF ratio;

Countries

China

Contacts

Public ContactZhang Ying

Affiliated Traditional Chinese Medicine Hospital of Xi'nan Medical University

1926063308@qq.com+86 135 5172 0908

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026