cervical spondylosis
Conditions
Interventions
titanium-coated group:Patients who meet the inclusion and exclusion criteria of this study and undergo anterior cervical discectomy and fusion using titanium-coated zero-profile interbody fusion devic
pure-PEEK group:Patients who meet the inclusion and exclusion criteria of this study and undergo anterior cervical discectomy and fusion using zero-profile PEEK interbody fusion devices.
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients aged 18 to 70 years, diagnosed with the following conditions, who are scheduled to undergo single-level ACDF and have signed an informed consent form: (1) cervical spondylotic myelopathy (2) cervical spondylotic radiculopathy (3) mixed cervical spondylosis (4) ossification of the posterior longitudinal ligament (OPLL) of the cervical spine (5) with or without mild cervical kyphosis (C2-7 Cobb angle < 10 degrees, kyphosis)
Exclusion criteria
Exclusion criteria: Patients with any of the following conditions will be excluded from the study: History of previous cervical spine surgery Patients scheduled for multi-segment cervical spine surgery Severe osteoporosis (CT value of cervical vertebrae 30) Mental or neurological disorders Liver, kidney, or hematological diseases with abnormal laboratory results Poor compliance Other surgical contraindications Substance abuse or alcoholism Participation in other clinical trials within the last three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fusion status of surgical segment;Implant subsidence; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cervical 3-7 range of motion (C3-7 ROM);Cervical 2-7 Cobb angle (C2-7 Cobb);Thoracic 1 Slope (T1 Slope);Cervical 2-7 sagittal vertical axis (C2-7 SVA);Neck pain;Cervical function;neurological function;Quality of life; | — |
Countries
China
Contacts
Public ContactZhou Feifei
Peking University Third Hospital
Outcome results
None listed