Gallbladder stones, cholecystitis, gallbladder polyps, cholelithiasis
Conditions
Interventions
Group O:Anesthesia induction : intravenous injection of midazolam 2mg, propofol 2mg / kg, oliceridine 0.06mg / kg , rocuronium 0.6mg / kg
Anesthesia maintenance : Remifentanil 4 ~ 8ug / ( kg /h ) and
Group S:Anesthesia induction : intravenous injection of midazolam 2 mg, propofol 2 mg / kg, sufentanil 0.3 µg / kg and rocuronium 0.6 mg / kg
Anesthesia maintenance : Remifentanil 4 ~ 8ug / ( kg/ h )
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years old; 2.ASA classification of ?-?; 3.BMI: 18-30kg/m^2 4.Patients scheduled for laparoscopic cholecystectomy day surgery under general anesthesia; 5.Subjects voluntarily participated and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Diseases of the nervous or mental system; 2.Serious abnormalities of liver and kidney function; 3.chronic pain; 4.long-term use of analgesic, sedative, antipsychotic drugs; 5. those who have participated in any clinical trial as a subject within 3 months prior to enrollment; 6. other conditions judged by the investigator to be unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 ( QoR-15 ) questionnaire scores at 24 hours after surgery.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic pressure(SBP);Diastolic blood pressure(DBP);Mean arterial pressure (MAP);SPO2;Heart rate(HR);Extubation time;Awakening time ;The incidence of adverse events related to analgesia (nausea, vomiting, respiratory depression, restlessness during awakening);Overall patient satisfaction score within 24 hours after surgery;Overall satisfaction rating of surgeons;The occurrence of major postoperative complications(e.g. lung infection);Numerical Rating Scale, NRS;Quality of Recovery-15 ( QoR-15 ) questionnaire scores at 72 hours after surgery.;Damage Index Score;hospitalization time; | — |
Countries
China
Contacts
Public ContactXiaohua Zou
Affiliated Hospital of Guizhou Medical University
Outcome results
None listed