Effective doses of ciprofol for laryngeal mask airway insertion combined with fentanyl in children: a dose finding study using biased-coin design up-and-down sequential method

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500095976

Enrollment

Unknown

Registered

2025-01-15

Start date

2025-04-01

Completion date

Unknown

Last updated

2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Toddlers group:Ciprofol for laryngeal mask airway insertion combined with?fentanyl in children

Children group:Ciprofol for laryngeal mask airway insertion combined with?fentanyl in children

Eligibility

Sex/Gender

All

Age

2 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. Selective minor surgery (operation duration <2 hours). 2. Aged 2 to 17 years. 3. No gender limit. 4. ASA grade I and II.

Exclusion criteria

Exclusion criteria: 1. The patient was obese. 2. The patient was complicated with difficult airway. 3. The patient had a recent history of acute upper respiratory tract infection, asthma, or gastroesophageal reflux disease. 4. The patient had a history of allergy to the experimental drug.

Design outcomes

Primary

Measure	Time frame
Effective doses of?ciprofol for laryngeal mask airway insertion combined with?fentanyl in children;	—

Secondary

Measure	Time frame
Vital signs;Laryngospasm;Upper airway injury;Bradycardia;Hypotension;Anaphylaxis;	—

Countries

China

Contacts

Public ContactZhang Ruidong

Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine

doctorruidong@163.com+86 189 1663 7626

Outcome results