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Clinical study of deep neuromuscular blockade during laparoendoscopic single-site (LESS) gynecological surgery

Clinical study of deep neuromuscular blockade during laparoendoscopic single-site (LESS) gynecological surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095963
Enrollment
Unknown
Registered
2025-01-15
Start date
2025-02-01
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine fibroids and cervical cancer

Interventions

Deep neuromuscular blockade group:Intraoperative maintenance of PTC 1-2
Moderate neuromuscular blockade:Intraoperative maintenance of TOF 1-2

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective single port laparoscopic gynecological operation; 2. General anesthesia; 3. ASA class I-III;

Exclusion criteria

Exclusion criteria: 1. Unable or refusing to sign informed consent 2. Those with abnormal cognitive function and inability to cooperate 3. History of previous abdominal surgery 4. Obese patients (BMI greater than 28 kg/m2) 5. Hepatic and renal insufficiency and neuromuscular diseases 6. Long-term chronic pain and preoperative opioid use 7. Have a mental illness such as anxiety or depression 8. Patients who have undergone chemotherapy or radiotherapy before surgery

Design outcomes

Secondary

MeasureTime frame
Tofr0.25 time;Post-operative pain score by VAS scale;The number of additional muscle relaxants required during the operation;Use of postoperative analgesics;Incidence of postoperative complications;

Primary

MeasureTime frame
Scale of surgical contidion;

Countries

China

Contacts

Public ContactShen Yiwei

the First Affiliated Hospital of Chongqing Medical University

26035190@qq.com+86 138 8302 5685

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026