Stroke/sensory dysfunction, motor dysfunction
Conditions
Interventions
Synchronous group:5 Hz rTMS + 25 rPMS
Central intervention group:5 Hz rTMS
Peripheral intervention group:25 Hz rPMS
Control group:Routine rehabilitation training
Sponsors
Jing'an District Central Hospital Of Shanghai
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with first unilateral subcortical stroke confirmed by computed tomography (CT) or magnetic resonance (MRI) examination of the head (the diagnosis conforms to the consensus of the "Diagnostic Points of Various Major Cerebrovascular Diseases in China 2019" formulated by the Cerebrovascular Epidemiology Group of the Chinese Medical Association Neurology Branch); 2. Patients >=18 years old; 3. The course of disease was 10 days to 12 months after the onset of stroke patients; 4. Hemisensory dysfunction (at least one of the superficial, proprioceptive and complex senses was impaired during screening); 5. The patient was stable with no serious complications; 6. No cognitive dysfunction, able to execute simple commands (simple mental state score MMSE>=27 points); 7. The patient received conservative treatment after the onset of the disease, and did not receive surgical treatment such as craniotomy; 8. Patients voluntarily participated in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of epilepsy or family history of epilepsy; 2. The patient has a metal implant or a pacemaker implant; 3. The patient has cognitive dysfunction; 4. Moderate to severe spasm in the extensor and flexor muscles of the wrist and hand of the affected limb (modified Ashworth score >=2); 5. serious medical diseases (liver and kidney insufficiency, etc.); 6. Can not complete the treatment cycle, compliance is not good; 7. communication difficulties, aphasia or serious dysarthria, hearing impairment; 8. Severe pain: visual analogue VAS scribing standard: 7-10 points; 9. The patient is pregnant, lactating or participating in other clinical trials at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Semmes Weinstein Monofilaments Examination, SWME;Two-Point Discrimination Test,2PD;FMA-SE; | — |
Secondary
| Measure | Time frame |
|---|---|
| FMA-UE;Em-NAS;MEP;CIMT; | — |
Countries
China
Contacts
Public ContactJia Jie
Huashan Hospital, Fudan University
Outcome results
None listed