Postoperative cognitive dysfunction
Conditions
Interventions
Observation group:None
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age> 60 years old; 2. For patients who plan to undergo general anesthesia, the operation time > 60 minutes.
Exclusion criteria
Exclusion criteria: 1. Allergy to anesthetic drugs; 2. Patients with known difficult airway and severe asthma; 3. History of sedative and analgesic drug use (or positive pre-test drug screening); 4. Nervous system diseases and mental diseases; 5. Pregnant patients; 6. Patients who refuse to participate in this experiment; 7. Cognitive dysfunction, severe auditory or visual impairment; 8. Other drug research is underway.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| EEG power spectrum;Cerebral oxygen saturation; | — |
Primary
| Measure | Time frame |
|---|---|
| Time mean Flow rate of median cerebral artery ;Peak systolic flow velocity of middle cerebral artery;End-diastolic flow velocity of middle cerebral artery;Resistance index of middle cerebral artery;Pulse index of middle cerebral artery;3D-CAM scale score;Weight;Total operation time; | — |
Countries
China
Contacts
Public ContactXiaoping Zhu
The First Affiliated Hospital of Nanchang University
Outcome results
None listed