Skip to content

Determination the ED90s of different concentrations of ropivacaine with dural puncture epidural (DPE) combined with programmed intermittent epidural (PIEB) for labor analgesia: A randomized sequential allocation study

Determination the ED90s of different concentrations of ropivacaine with dural puncture epidural (DPE) combined with programmed intermittent epidural (PIEB) for labor analgesia: A randomized sequential allocation study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095945
Enrollment
Unknown
Registered
2025-01-15
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain during laboring

Interventions

Sponsors

Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an)
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) Singleton full-term pregnancies aged 18-40 years old (including primiparous and multiparous women) who are undergoing neuraxial analgesia and undergoing labor analgesia; (2) Cervical dilation 5 points; (3) ASA grading I-II

Exclusion criteria

Exclusion criteria: (1) Neuraxial analgesia contraindication; (2) Hypertension (including chronic hypertension; gestational hypertension and preeclampsia); (3) gestational diabetes; (4) macrosomia; (5) body mass index; (6).BMI>=40kg/m^2; (7) fetal distress; (8) Those who use other methods for analgesia; (9) Ropivacaine or sufentanil contraindicated.

Design outcomes

Primary

MeasureTime frame
The ED90s of different concentrations of ropivacaine with dural puncture epidural (DPE) combined with programmed intermittent epidural (PIEB);

Secondary

MeasureTime frame
visual analogue scale (VAS) score;Bromage score;Apgar score;adverse event;

Countries

China

Contacts

Public ContactXiangsheng Xiong

Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an)

158193942@qq.com+86 177 9898 2001

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026