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The Impact of SOFA Score Trajectories on Prognostic Evaluation of Patients with Acute Necrotizing Pancreatitis

Analysis of Risk Factors for Mortality in Patients with Acute Necrotizing Pancreatitis (ANP) and the Impact of SOFA Score Trajectories on Prognostic Subgroup Classification

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095939
Enrollment
Unknown
Registered
2025-01-15
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Necrotizing Pancreatitis (ANP)

Interventions

Organ function deterioration group:NA
Mild organ dysfunction group:NA
The group of Improvement after organ function deterioration:NA

Sponsors

First People's Hospital of Huzhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. There are general clinical manifestations related to pancreatitis, such as middle and upper abdominal pain, abdominal distension, nausea and vomiting; 2. Elevated serum lipase or serum amylase (>3 times the upper limit of normal) or urinary trypsinogen >50ng/mL; 3. Typical imaging findings of pancreatic necrosis indicated by abdominal B-ultrasound and abdominal CT or bacterial culture of necrotic tissue caused by fine needle aspiration or drainage were positive; 4. Duration of organ failure (Marshall score >=2) >48h;

Exclusion criteria

Exclusion criteria: 1. Under 18 years of age; 2. The hospital stay was less than 7 days; 3. Pregnant and lactating women; 4. The survival time after diagnosis of ANP is less than 24 hours; 5. serious primary heart, liver, lung, kidney and blood diseases; 6. Patients with advanced cancer and cachexia;

Design outcomes

Primary

MeasureTime frame
Sequential Organ Failure Assessment (SOFA) score;Laboratory tests;underlying disease;the outcome of the disease;Treatment for pancreatitis;

Secondary

MeasureTime frame
Demographic data;

Countries

China

Contacts

Public ContactLi Zhong

First People's Hospital of Huzhou

51103@zjhu.edu.cn+86 13757061864

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026