Sufentanil-induced cough
Conditions
Interventions
Experimental group:1.5 mg of oliceridine is diluted to 5 ml intravenously for 1 min before induction
Control group:Normal saline 5ml slow intravenous injection
Sponsors
The Second People's Hospital of Hefei
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) ASA anesthesia classification I.~II.; (2) The patient was 18 years old<= age <= 65 years old, BMI: 18-25kg/m²; (3) Patients undergoing elective general anesthesia surgery (4) The patients voluntarily participated in this study and had signed the informed consent form before surgery.
Exclusion criteria
Exclusion criteria: (1) Patients who are allergic to oliceridine and other anesthetic drugs; (2) History of severe postoperative nausea and vomiting; (3) Patients with impaired language, intelligence, comprehension and inability to communicate normally; (4) Patients with a history of neuropsychiatric disorders, drug dependence, and alcoholism; (5) Patients with severe cardiovascular and cerebrovascular diseases or preoperative dysfunction of major organs; (6) The patient's electrocardiogram is abnormal, such as QT interval prolongation >450ms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Choking score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Heart rate;Pulse oximetry; | — |
Countries
China
Contacts
Public ContactQuanmin Chen
The Second People's Hospital of Hefei
Outcome results
None listed