postoperative nausea and vomiting
Conditions
Interventions
group A:dolasetron
group B:dolasetron+dexamethasone
group C:transcutaneous electrical acupoint stimulation+dolasetron
group D: transcutaneous electrical acupoint stimulation+dolasetron+dexamethasone
Sponsors
Qingdao Municipal Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing gynecological laparoscopic surgery 2. ASA grade: ?~?; 3. Age: 18-65 years; 4. Patients were informed of this study and signed informed consent to voluntarily cooperate with this study 5. Patients who are not allergy to narcotic drugs or drugs used in the study; 6. All included patients had not take any antiemetic medication in the 7 days prior to surgery: 7. Patients are informed about this study and sign the informed consent form, and voluntarily cooperate with this study; 8. Patients with no history of allergic reaction to narcotic drugs and drugs used in the study.
Exclusion criteria
Exclusion criteria: 1. Allergy to metal, or have pacemakers,metal implants, etc; 2. Skin damaged at the wrists; 3. Mental disorder or cognitive impairment, can't communicate normally; 4. History of major trauma or surgery 5. History of chemotherapy within 4 weeks or radiotherapy within 8 weeks; 6. Have used steroid hormone or other antiemetic drugs within 1 week; 7. A history of opioid or alcohol addiction; 8. Liver and kidney dysfunction; 9. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| frequency and degree of postoperative nausea and vomiting ;use of metoclopramide for antiemesis after sugery;The combined use of drugs during and after operation;Occurrence of dizziness, headache, hypertension and hypotension after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation time, infusion volume and blood loss;Occurrence of hypotension and hypertension during operation; | — |
Countries
China
Contacts
Public ContactLiu Junchao
Qingdao Municipal Hospital
Outcome results
None listed