Infectious wounds
Conditions
Interventions
Cold plasma therapy group:After the routine treatment of outpatient patients, the cold plasma treatment system independently developed by Nanjing University of Aeronautics and Astronautics was used, a
After continuous intervention on the wound for 7 days, the infection and healing of the wound in the intervention group and the control group were compared.
Conventional treatment group:Follow the standard treatment of burn wound infection provided in "Expert Consensus on the Treatment of second-degree Burn Wound (2024 edition) -- Prevention and Treatment
Sponsors
General Hospital of Eastern Theater Command, PLA
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients (18-70 years old). 2. Burn wound with infection. 3. The burn area of the total body area does not exceed 10% of the body surface area, and the test wound area is less than 80cm2. 4. The burn occurred on a limb or torso. 5. Informed consent has been signed.
Exclusion criteria
Exclusion criteria: 1.Patients with serious comorbidities, such as heart disease, diabetes, kidney disease, immune system disease, etc. 2.Patients with systemic infection and serious infection other than the burn area, such as patients with lung infection and urinary system infection. 3. Patients with cognitive impairment or mental illness. 4. Patients with high blood risk: long-term oral anticoagulant drugs; Severe or end-stage chronic kidney disease (EGFR <30 ml/min); Moderate or severe anemia; Spontaneous bleeding (or recurrent episodes) that requires hospitalization and/or blood transfusion within 6 months; Moderate or severe thrombocytopenia; Chronic hemorrhagic constitution; Cirrhosis with portal hypertension; Active malignancy within the past 12 months; History of intracranial hemorrhage; Traumatic intracranial hemorrhage in the past 12 months; Cerebral arteriovenous malformation; Moderate or severe ischemic stroke within the past 6 months (NIHSS=5); Long-term dual antiplatelet therapy. 5. Those who had a birth plan during the trial or within 3 months after the trial ended (including male subjects). 6. Patients with difficulty in venous blood collection. 7. Patients do not cooperate with treatment.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Local wound area;Wound healing time;Local pathogenic bacterial load and drug susceptibility;Changes in systemic inflammatory response and immune cells;Rate reduction in wound area; | — |
Primary
| Measure | Time frame |
|---|---|
| Whether the wound is healed;Wound healing rate; | — |
Countries
China
Contacts
Public ContactLi Weiqin
General Hospital of Eastern Theater Command, PLA
Outcome results
None listed