Postherpetic neuralgia
Conditions
Interventions
Experimental group:Pregabalin and Duloxetine
Control subjects:pregabalin
Sponsors
Affiliated Hospital of Shandong Second Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. History of herpes zoster; 2. Pain numerical rating scale (NRS) score >= 4; 3. Age > 18 years old; 4. Can cooperate with the completion of pain, sleep quality and other scales assessment.
Exclusion criteria
Exclusion criteria: 1.Combined with heart, brain, liver, kidney and other systems of serious primary diseases and critical condition is difficult to tolerate treatment; 2.Combined with serious mental and psychological disorders can not cooperate; 3.Coagulation dysfunction; 4.Allergic to therapeutic drugs; 5 Affected parts of the nerves have been neurodestructive surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numerical rating scale, NRS;Adverse effects; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuropathic pain symptom inventory, NPSI;Mechanical allodynia;Mechanical Pain Threshold, MPT;Hospital Anxiety and Depression Scale, HADS;The Short-From-36 Health Survey, SF-36; | — |
Countries
China
Contacts
Public ContactRen Zhanjie
Affiliated Hospital of Shandong Second Medical University
Outcome results
None listed