Perioperative hypotension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Subjects who were scheduled to undergo double-hole thoracoscopic lobectomy were 18-65 years old, ASA grade I to III, BMI 18-30 kg/m^2.
Exclusion criteria
Exclusion criteria: 1.Severe hypertension (systolic blood pressure >= 180 mmHg or diastolic blood pressure >= 110 mmHg); 2.MAP < 70mmHg before anesthesia induction; 3.emergency surgery; 4.severe cardiovascular disease (history of brain or thoracic/abdominal aortic aneurysm); 5.congestive heart failure, i.e., New York Heart Association classification III or IV; 6.untreated or unstable ischemic heart disease; 7.history of severe aortic or mitral valve disease; 8.pregnant or lactating women; 9.abnormal coagulation function; 10.sepsis, septicemia, or infection at the puncture site; 11.allergy to any of the drugs involved in the trial; 12.neurological or spinal disorders (deformity or trauma, surgical history), abnormal skin sensation in the thoracic and back; 13.difficulty in airway management; 14.or determined by the investigator to be ineligible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of severe hypotension;VAS scores at rest and exercise (cough) 4 and 24 hours after surgery;Use of vasoactive drugs during induction;Intraoperative use of propofol and remifentanil;Anesthesia time, intraoperative intravenous infusion volume, intraoperative urine volume, intraoperative blood loss, extubation time;Puncture related adverse events;Analgesic pump usage within 24 hours;QOR-40 score 24 hours after surgery;The patient experienced puncture related complications within 72 hours after surgery;Satisfaction survey 72 hours after operation; | — |
Countries
China
Contacts
NanJing First Hospital