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The value of nutritional and inflammatory markers in peripheral blood in predicting the efficacy and complications of immunotherapy for advanced cholangiocarcinoma

The value of nutritional and inflammatory markers in peripheral blood in predicting the efficacy and complications of immunotherapy for advanced cholangiocarcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095900
Enrollment
Unknown
Registered
2025-01-15
Start date
2025-02-01
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholangiocarcinoma

Interventions

Nutrition-inflammation index low-risk group:None
Nutrition-inflammation index high-risk group:None

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) pathologically confirmed advanced cholangiocarcinoma; (2) patients aged 18-80 years; (3) The TNM stage of the tumor was stage III-IV according to the 8th edition of the American Joint Committee on Cancer staging system. (4) unable to undergo radical resection and receiving at least 2 courses of immunotherapy; (5) Routine blood test, liver and kidney function tests were performed within two weeks before the first immunotherapy. (6) No serious complications of heart, liver, kidney and other important organs; (7) complete clinical and laboratory data were available.

Exclusion criteria

Exclusion criteria: (1) complicated with other malignant tumors and important organ dysfunction; (2) presence of bleeding or acute or chronic infection; (3) patients with pulmonary embolism, acute myocardial infarction or cerebrovascular disease; (4) patients with active autoimmune disease or severe immunodeficiency.

Design outcomes

Primary

MeasureTime frame
Overall survival;

Secondary

MeasureTime frame
Recurrence-free survival;

Countries

China

Contacts

Public ContactHaitao Zhao

Peking Union Medical College Hospital

zhaoht@pumch.cn+86 139 0124 6374

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026