dermatophytosis
Conditions
Interventions
Cold plasma therapy group:After the patients completed the routine treatment, the cold plasma treatment system independently developed by Nanjing University of Aeronautics and Astronautic was used. Ea
Conventional treatment group:The standard treatment regimen was provided in the Chinese Guidelines for the Diagnosis and treatment of Tinea corporis and Tinea cruris (Primary Practice Edition 2022) an
Sponsors
General Hospital of Eastern Theater Command, PLA
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for tinea pedis and tinea cruris (at the same time meet the following 2 items) : 1) Typical clinical manifestations: the primary lesion was papules, blisters or papuloherpes, semi-annular erythema with clear boundary and obvious inflammation extending from the medial thigh to the outside, covered with scales, and subjective itching. 2) Positive fungal microscopic examination and/or dermatophytes isolated by culture; 2.Adult patients (18-70 years old). 3. All subjects voluntarily participated in the study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: Patients with tinea pedis and tinea cruris treated with antifungal agents within 1.2 weeks. 2. Patients with serious comorbidities, such as heart disease, diabetes, kidney disease, immune system disease, etc. 3. Patients with systemic infection or serious infection other than burn, such as pulmonary infection, urinary system infection, etc. 4. Patients with cognitive impairment or psychiatric disorders. 5. Those who plan to have children during or within 3 months after the trial (including male subjects). 6. Patients with difficulty in venous blood collection. 7. Systemic use of anti-HIV protease inhibitors and antineoplastic chemotherapy drugs, organ transplant immunosuppressants and glucocorticoids. 8. The patient is not cooperating with treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Microscopic Examination of fungi; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound healing time;Systemic inflammatory response and changes in immune cells; | — |
Countries
China
Contacts
Public ContactLi Weiqin
General Hospital of Eastern Theater Command, PLA
Outcome results
None listed