Interstitial Lung Disease
Conditions
Interventions
ILAs Cohort:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: Participants > 40 years of age who have lung abnormalities found on chest CT on physical examination that meet the diagnostic criteria for ILAs (non-falling interstitial lung abnormalities involving at least 5% of any lung area (ground-glass opacity, reticular opacity, structural distortion, traction bronchiectasis, honeycomb and non-emphysematous cyst)) are incidentally found on chest imaging in people with unsuspected ILD.
Exclusion criteria
Exclusion criteria: 1. Participants with diagnosis of CTD, ILD; 2. Signs of ILAs were considered in study participants associated with heart failure; 3. Participants who are unwilling to cooperate with participation in follow-up visits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of ILAs progress to ILD ;The proportion of ILAs with radiological progression;The proportion of ILAs showing significant decline in lung function (with an annual decline in FVC% predicted >=5% absolute value);The proportion of ILAs progress to other lung diseases;The mortality rate of ILAs during the follow-up period;The proportion of ILAs combined with other lung diseases (pulmonary nodule,lung cancer, pulmonary emphysema, COPD);Clinical Characteristics;Pulmonary Function Tests;Six Minute Walk Test;Blood Tests (routine, biochemistry, immuno-related, KL6);Chest CT; | — |
Countries
China
Contacts
Public ContactFengming Luo
West China Hospital, Sichuan University
Outcome results
None listed